Featured in
Journal of Neuroscience 

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Elevated Lamin B1 in Neurons Made from Human Dystonia Cells

Baojin Ding, Yu Tang, Shuaipeng Ma, Masuma Akter, Meng-Lu Liu, et al.

 

(see pages 2024–2038)

Lab Updates

 

  • August 5, 2021

Congratulations to Masuma for receiving the Student Government Association (SGA) International Friendship Non-Endowed Scholarship for the 2021-2022 school year from UL Lafayette.

  • July 21, 2021

Congratulations to Casey for passing his Master proposal defense! 

  • July 2, 2021

Congratulations to Masuma for passing her Ph.D. proposal defense!

  • February 12, 2020

Congratulations to the Ding Lab on receiving a grant from the National Institutes of Health (NIH). This is the National Institute of Neurological Disorders and Stroke (NINDS) Exploratory Neuroscience Research Grant. The project aims to determine the pathogenesis of childhood-onset DYT1 dystonia in patient-specific neurons that are generated by direct conversion and iPSC-based reprogramming and differentiation.

  • November 15, 2019

Congratulations to the Ding Lab on receiving a grant from the Department of Defense (DoD) Peer-Reviewed Medical Research Program (PRMRP) Discovery Award. This project aims to determine the pathogenesis of adulthood onset dystonia via directly reprogramming human neurons from patient fibroblasts. 

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A

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B

Figure: Lamin B1 (green) is localized to the nucleus (blue) in motor neurons (red) derived from control human fibroblasts (A), but is mislocalized to the neurites of neurons derived from DYT1 patient fibroblasts (B). See Ding et al for details.

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